PhD Molecular Pharmacology

Course Overview This PhD program offers world-class training in molecular pharmacology with a specialized focus on G protein-coupled receptors (GPCRs), the most successful drug target class in history. Students will join a large, internationally recognized research group to employ multi-disciplinary, 'molecule to behaviour' approaches, from pharmacological analysis and drug discovery to the use of transgenic disease models. The research is directly linked to major pharmaceutical companies and has a proven track record of therapeutic translation and commercial spin-out. Key Program Highlights Focus on therapeutically relevant GPCRs, which are the target of one-third of all approved drugs. Multi-disciplinary training encompassing pharmacological analysis, cell signalling, and transgenic mouse models. Direct links to major pharmaceutical companies (e.g., AstraZeneca, Eli Lilly) and opportunities for collaboration. Proven translational success with the spin-out company Caldan Therapeutics and significant Series A funding. Pioneering work on 'hard to target' receptors and innovative techniques like Designer Receptors Exclusively Activated by Designer Drugs (DREADDs).